Connectivity and expression in protein networks: Proteins in a complex are uniformly expressed

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dc.creatorCarmi, Shai
dc.creatorLevanon, Erez Y.
dc.creatorHavlin, Shlomo
dc.creatorEisenberg, Eli
dc.date2005-08-17
dc.date2006-01-26
dc.date.accessioned2026-07-07T06:43:30Z
dc.date.available2026-07-07T06:43:30Z
dc.descriptionWe explore the interplay between the protein-protein interactions network and the expression of the interacting proteins. It is shown that interacting proteins are expressed in significantly more similar cellular concentrations. This is largely due to interacting pairs which are part of protein complexes. We solve a generic model of complex formation and show explicitly that complexes form most efficiently when their members have roughly the same concentrations. Therefore, the observed similarity in interacting protein concentrations could be attributed to optimization for efficiency of complex formation.
dc.descriptionrevised version; accepted for publication in PRE
dc.identifierhttps://arxiv.org/abs/q-bio/0508021
dc.identifierhttp://arxiv.org/abs/q-bio/0508021
dc.identifierPhys. Rev. E 73, 031909 (2006)
dc.identifierdoi:10.1103/PhysRevE.73.031909
dc.identifier.urihttp://salesiana.dossiersoluciones.com/handle/123456789/102439
dc.subjectMolecular Networks
dc.subjectOther Condensed Matter
dc.subjectOther Quantitative Biology
dc.titleConnectivity and expression in protein networks: Proteins in a complex are uniformly expressed
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