Au-Ag template stripped pattern for scanning probe investigations of DNA arrays produced by Dip Pen Nanolithography

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dc.creatorBaserga, Andrea
dc.creatorVigano', Marco
dc.creatorCasari, Carlo S.
dc.creatorTurri, Stefano
dc.creatorBassi, Andrea Li
dc.creatorLevi, Marinella
dc.creatorBottani, Carlo E.
dc.date2008-09-15
dc.date.accessioned2026-07-07T10:19:22Z
dc.date.available2026-07-07T10:19:22Z
dc.descriptionWe report on DNA arrays produced by Dip Pen Nanolithography (DPN) on a novel Au-Ag micro patterned template stripped surface. DNA arrays have been investigated by atomic force microscopy (AFM) and scanning tunnelling microscopy (STM) showing that the patterned template stripped substrate enables easy retrieval of the DPN-functionalized zone with a standard optical microscope permitting a multi-instrument and multi-technique local detection and analysis. Moreover the smooth surface of the Au squares (abput 5-10 angstrom roughness) allows to be sensitive to the hybridization of the oligonucleotide array with label-free target DNA. Our Au-Ag substrates, combining the retrieving capabilities of the patterned surface with the smoothness of the template stripped technique, are candidates for the investigation of DPN nanostructures and for the development of label free detection methods for DNA nanoarrays based on the use of scanning probes.
dc.descriptionLangmuir (accepted)
dc.identifierhttps://arxiv.org/abs/0809.2545
dc.identifierhttp://arxiv.org/abs/0809.2545
dc.identifierLangmuir 24, 13212-13217 (2008)
dc.identifierdoi:10.1021/la801903u
dc.identifier.urihttp://salesiana.dossiersoluciones.com/handle/123456789/174480
dc.subjectSoft Condensed Matter
dc.titleAu-Ag template stripped pattern for scanning probe investigations of DNA arrays produced by Dip Pen Nanolithography
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