Stretching of proteins in a force-clamp

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dc.creatorSzymczak, Piotr
dc.creatorCieplak, Marek
dc.date2005-12-01
dc.date.accessioned2026-07-07T06:56:24Z
dc.date.available2026-07-07T06:56:24Z
dc.descriptionMechanically induced protein unfolding in the force-clamp apparatus is shown, in a coarse-grained model of ubiquitin, to have lognormal statistics above a treshold force and exponential below it. Correspondingly, the mean unfolding time is slowly varying and exponentially decreases as a function of the force. The time dependencies of the end-to-end distances are also distinct. The time sequence of unfolding events weakly depends on force and much of it resembles that for stretching at constant speed. A more complicated time dependence arises for integrin.
dc.description14 pages, 6 figures; submitted to J. Phys. Cond. Matt
dc.identifierhttps://arxiv.org/abs/q-bio/0512004
dc.identifierhttp://arxiv.org/abs/q-bio/0512004
dc.identifier.urihttp://salesiana.dossiersoluciones.com/handle/123456789/106626
dc.subjectBiomolecules
dc.subjectSoft Condensed Matter
dc.titleStretching of proteins in a force-clamp
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