Nanobiosensors based on individual olfactory receptors

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In the SPOT-NOSED European project, nanoscale sensing elements bearing olfactory receptors and grafted onto functionalized gold substrates are used as odorant detectors to develop a new concept of nanobioelectronic nose, through sensitive impedancemetric measurement of single receptor conformational change upon ligand binding, with a better specificity and lower detection threshold than traditional physical sensors.
Submitted on behalf of EDA Publishing Association (http://irevues.inist.fr/EDA-Publishing)

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