Probability distribution of bubble lengths in DNA

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dc.creatorAres, S.
dc.creatorKalosakas, G.
dc.date2006-07-05
dc.date2007-02-16
dc.date.accessioned2026-07-07T07:47:08Z
dc.date.available2026-07-07T07:47:08Z
dc.descriptionThe distribution of bubble lengths in double-stranded DNA is presented for segments of varying guanine-cytosine (GC) content, obtained with Monte Carlo simulations using the Peyrard-Bishop-Dauxois model at 310 K. An analytical description of the obtained distribution in the whole regime investigated, i.e., up to bubble widths of the order of tens of nanometers, is available. We find that the decay lengths and characteristic exponents of this distribution show two distinct regimes as a function of GC content. The observed distribution is attributed to the anharmonic interactions within base pairs. The results are discussed in the framework of the Poland-Scheraga and the Peyrard-Bishop (with linear instead of nonlinear stacking interaction) models.
dc.description5 pages, 4 figures, accepted version. The distribution obtained from the Peyrard-Bishop-Dauxois model is now fitted and discussed in the framework of the Poland-Scheraga model
dc.identifierhttps://arxiv.org/abs/q-bio/0607009
dc.identifierhttp://arxiv.org/abs/q-bio/0607009
dc.identifierNano Lett., 7 (2), 307 -311, 2007
dc.identifierdoi:10.1021/nl062304a
dc.identifier.urihttp://salesiana.dossiersoluciones.com/handle/123456789/124061
dc.subjectBiomolecules
dc.subjectStatistical Mechanics
dc.subjectBiological Physics
dc.titleProbability distribution of bubble lengths in DNA
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