Subnetwork hierarchies of biochemical pathways

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dc.creatorHolme, Petter
dc.creatorHuss, Mikael
dc.creatorJeong, Hawoong
dc.date2002-06-17
dc.date.accessioned2026-07-07T02:45:52Z
dc.date.available2026-07-07T02:45:52Z
dc.descriptionWe present a method to decompose biochemical networks into subnetworks based on the global geometry of the network. This method enables us to analyse the full hierarchical organisation of biochemical networks and is applied to 43 organisms from the WIT database. Two types of biochemical networks are considered: metabolic networks and whole-cellular networks (also including e.g. information processes). Conceptual and quantitative ways of describing the hierarchical ordering are discussed. The general picture of the metabolic networks arising from our study is that of a few core-clusters centred around the most highly connected substances enclosed by other substances in outer shells, and a few other well-defined subnetworks.
dc.description9 pages, color, submitted to Bioinformatics
dc.identifierhttps://arxiv.org/abs/cond-mat/0206292
dc.identifierhttp://arxiv.org/abs/cond-mat/0206292
dc.identifierBioinformatics 19, 532-538 (2003)
dc.identifierdoi:10.1093/bioinformatics/btg033
dc.identifier.urihttp://salesiana.dossiersoluciones.com/handle/123456789/19457
dc.subjectDisordered Systems and Neural Networks
dc.subjectMolecular Networks
dc.titleSubnetwork hierarchies of biochemical pathways
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