Chance and necessity in chromosomal gene distributions

Simple item page
dc.creatorHermsen, Rutger
dc.creatorWolde, Pieter Rein ten
dc.creatorTeichmann, Sarah
dc.date2008-03-08
dc.date.accessioned2026-07-07T09:25:52Z
dc.date.available2026-07-07T09:25:52Z
dc.descriptionBy analyzing the spacing of genes on chromosomes, we find that transcriptional and RNA-processing regulatory sequences outside coding regions leave footprints on the distribution of intergenic distances. Using analogies between genes on chromosomes and one-dimensional gases, we constructed a statistical null model. We have used this to estimate typical upstream and downstream regulatory sequence sizes in various species. Deviations from this model reveal bi-directional transcriptional regulatory regions in S. cerevisiae and bi-directional terminators in E. coli.
dc.descriptionMain text plus supplementary text; 26 pages, 7 figures in total. To appear in TRENDS in Genetics (May 2008)
dc.identifierhttps://arxiv.org/abs/0803.1261
dc.identifierhttp://arxiv.org/abs/0803.1261
dc.identifier.urihttp://salesiana.dossiersoluciones.com/handle/123456789/156554
dc.subjectGenomics
dc.titleChance and necessity in chromosomal gene distributions
dc.typetext

Files

Collections

arXiv