Simulation of Multicellular Tumor Spheroids Growth Dynamics

Brutovsky, Branislav; Horvath, Denis; Lisy, Vladimir

Simulation of Multicellular Tumor Spheroids Growth Dynamics

Authors

Brutovsky, Branislav

Horvath, Denis

Lisy, Vladimir

Description

The inverse geometric approach to the modeling of the growth of circular objects revealing required features, such as the velocity of the growth and fractal behavior of their contours, is presented. It enables to reproduce some of the recent findings in morphometry of tumors with the possible implications for cancer research. The technique is based on cellular automata paradigm with the transition rules selected by optimization procedure performed by the genetic algorithms.
6 pages, 7 figures