Are scale-free regulatory networks larger than random ones?
| dc.creator | Fortuna, Miguel A. | |
| dc.creator | Melian, Carlos J. | |
| dc.date | 2005-01-19 | |
| dc.date.accessioned | 2026-07-07T05:58:53Z | |
| dc.date.available | 2026-07-07T05:58:53Z | |
| dc.description | Network of packages with regulatory interactions (dependences and conflicts) from Debian GNU/Linux operating system is compiled and used as analogy of a gene regulatory network. Using a trace-back algorithm we assembly networks from the potential pool of packages for both scale-free and exponential topology from real and a null model data, respectively. We calculate the maximum number of packages that can be functionally installed in the system (i.e., the active network size). We show that scale-free regulatory networks allow a larger active network size than random ones. Small genomes with scale-free regulatory topology could allow much more functionality than large genomes with an exponential one, with implications on its dynamics, robustness and evolution. | |
| dc.description | Submitted to Phys. Rev. Lett | |
| dc.identifier | https://arxiv.org/abs/q-bio/0501027 | |
| dc.identifier | http://arxiv.org/abs/q-bio/0501027 | |
| dc.identifier.uri | http://salesiana.dossiersoluciones.com/handle/123456789/88528 | |
| dc.subject | Genomics | |
| dc.subject | Molecular Networks | |
| dc.title | Are scale-free regulatory networks larger than random ones? | |
| dc.type | text |