Efficiency of DNA replication in the Polymerase Chain Reactio

Simple item page
dc.creatorCecchi, Guillermo A.
dc.creatorStolovitzky, Gustavo
dc.date2001-05-04
dc.date.accessioned2026-07-07T02:41:18Z
dc.date.available2026-07-07T02:41:18Z
dc.descriptionWe present a detailed kinetic model for the Polymerase Chain Reaction, and model the probability of replication in terms of the physical parameters of the problem. Applying the theory of branching processes, we show the existance of a new phenomenon affecting the probability distribution function of the number of replicants: for small number of initial molecules, the limiting behavior (with increasing number of cycles) of the pdf is represented by a multi-modal funtion.
dc.description4 figures
dc.identifierhttps://arxiv.org/abs/cond-mat/0105099
dc.identifierhttp://arxiv.org/abs/cond-mat/0105099
dc.identifierProceedings of the National Academy of Sciences Volume 93, Number 23; Pages 12947-12952, November 12, 1996
dc.identifier.urihttp://salesiana.dossiersoluciones.com/handle/123456789/17694
dc.subjectStatistical Mechanics
dc.subjectSoft Condensed Matter
dc.subjectQuantitative Biology
dc.titleEfficiency of DNA replication in the Polymerase Chain Reactio
dc.typetext

Files

Collections

arXiv