Role-similarity based functional prediction in networked systems: Application to the yeast proteome

dc.creatorHolme, Petter
dc.creatorHuss, Mikael
dc.date2005-03-06
dc.date.accessioned2026-07-07T06:21:40Z
dc.date.available2026-07-07T06:21:40Z
dc.descriptionWe propose a general method to predict functions of vertices where: 1. The wiring of the network is somehow related to the vertex functionality. 2. A fraction of the vertices are functionally classified. The method is influenced by role-similarity measures of social network analysis. The two versions of our prediction scheme is tested on model networks were the functions of the vertices are designed to match their network surroundings. We also apply these methods to the proteome of the yeast Saccharomyces cerevisiae and find the results compatible with more specialized methods.
dc.identifierhttps://arxiv.org/abs/q-bio/0503010
dc.identifierhttp://arxiv.org/abs/q-bio/0503010
dc.identifierJ. Roy. Soc. Interface 2, 327 (2005)
dc.identifierdoi:10.1098/rsif.2005.0046
dc.identifier.urihttp://salesiana.dossiersoluciones.com/handle/123456789/95668
dc.subjectMolecular Networks
dc.subjectOther Condensed Matter
dc.subjectOther Quantitative Biology
dc.titleRole-similarity based functional prediction in networked systems: Application to the yeast proteome
dc.typetext

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