Tightening of knots in proteins

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We perform theoretical studies of stretching of 20 proteins with knots within a coarse grained model. The knot's ends are found to jump to well defined sequential locations that are associated with sharp turns whereas in homopolymers they diffuse around and eventually slide off. The waiting times of the jumps are increasingly stochastic as the temperature is raised. Larger knots do not return to their native locations when a protein is released after stretching.
4 pages, 5 figures

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Biomolecules, Soft Condensed Matter

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http://salesiana.dossiersoluciones.com/handle/123456789/157713

Consulte el texto completo en el siguiente enlace:

https://arxiv.org/abs/0706.2380
 http://arxiv.org/abs/0706.2380
 Phys. Rev. Lett. 100, 058106 (2008)
 doi:10.1103/PhysRevLett.100.058106

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arXiv