Small Angle Scattering and Zeta Potential of Liposomes Loaded with Octa(carboranyl)porphyrazine

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dc.creatorSalvati, Anna
dc.creatorRistori, Sandra
dc.creatorOberdisse, Julian
dc.creatorSpalla, Olivier
dc.creatorRicciardi, Giampaolo
dc.creatorPietrangeli, Daniela
dc.creatorGiustini, Mauro
dc.creatorMartini, Giacomo
dc.date2007-09-06
dc.date.accessioned2026-07-07T08:27:55Z
dc.date.available2026-07-07T08:27:55Z
dc.descriptionIn this work the physicochemical characterization of liposomes loaded with a newly synthesised carboranyl porphyrazine (H2HECASPz) is described. This molecule represents a potential drug for different anticancer therapies, such as Boron Neutron Capture Therapy, Photodynamic Therapy and Photothermal Therapy. Different loading methods and different lipid mixtures were tested. The corresponding loaded vectors were studied by Small Angle Scattering (SANS and SAXS), light scattering and zeta potential. The combined analysis of structural data at various length scales and the measurement of the surface charge allowed to obtain a detailed characterization of the investigated systems. The mechanisms underlying the onset of differences in relevant physicochemical parameters (size, polydispersity and charge) were also critically discussed.
dc.identifierhttps://arxiv.org/abs/0709.0830
dc.identifierhttp://arxiv.org/abs/0709.0830
dc.identifierThe Journal of Physical Chemistry B 111 (2007) 10357-10364
dc.identifierdoi:10.1021/jp0731710
dc.identifier.urihttp://salesiana.dossiersoluciones.com/handle/123456789/137435
dc.subjectSoft Condensed Matter
dc.subjectBiological Physics
dc.titleSmall Angle Scattering and Zeta Potential of Liposomes Loaded with Octa(carboranyl)porphyrazine
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