Optimal Mutation Rates on Static Fitness Landscpes

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dc.creatorNilsson, M.
dc.date2000-05-08
dc.date.accessioned2026-07-07T05:44:05Z
dc.date.available2026-07-07T05:44:05Z
dc.descriptionWe study the evolution of mutation rates for an asexual population living on a static fitness landscape, consisting of multiple peaks forming an evolutionary staircase. The optimal mutation rate is found by maximizing the diffusion towards higher fitness. Surprisingly the optimal genomic copying fidelity is given by Q = e^(-1/ln(n)) (where n is the genome length), independent of all other parameters in the model. Simulations confirm this theoretical result. We also discuss the relation between the optimal mutation rate on static and dynamic fitness landscapes.
dc.description4 pages, 5 figures
dc.identifierhttps://arxiv.org/abs/physics/0005018
dc.identifierhttp://arxiv.org/abs/physics/0005018
dc.identifier.urihttp://salesiana.dossiersoluciones.com/handle/123456789/83497
dc.subjectBiological Physics
dc.subjectQuantitative Biology
dc.titleOptimal Mutation Rates on Static Fitness Landscpes
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