Towards comparative theoretical neuroanatomy of the cerebral cortex
Abstract
Description
Despite differences in brain sizes and cognitive niches among mammals, their cerebral cortices posses many common features and regularities. These regularities have been a subject of experimental investigation in neuroanatomy for the last 100 years. It is believed that such studies may provide clues about cortical design principles and perhaps function. However, on a theoretical side there has been little interest, until recently, in studying quantitatively these regularities. This article reviews some attempts in this direction with an emphasis on neuronal connectivity. It is suggested that the brain development is influenced by different, conflicting in outcome, functional/biochemical constraints. Because of these conflicting constraints, it is hypothesized that the architecture of the cerebral cortex is shaped by some global optimization plan.
To be published in "Journal of Integrative Neuroscience"; special issue on 'Neuromorphic models'
To be published in "Journal of Integrative Neuroscience"; special issue on 'Neuromorphic models'