Mathematical modeling of filamentous microorganisms

Simple item page
dc.creatorBezzi, Michele
dc.creatorCiliberto, Andrea
dc.date2004-02-03
dc.date.accessioned2026-07-07T05:58:10Z
dc.date.available2026-07-07T05:58:10Z
dc.descriptionGrowth patterns generated by filamentous organisms (e.g. actinomycetes and fungi) involve spatial and temporal dynamics at different length scales. Several mathematical models have been proposed in the last thirty years to address these specific dynamics. Phenomenological macroscopic models are able to reproduce the temporal dynamics of colony-related quantities (e.g. colony growth rate) but do not explain the development of mycelial morphologies nor the single hyphal growth. Reaction-diffusion models are a bridge between macroscopic and microscopic worlds as they produce mean-field approximations of single-cell behaviors. Microscopic models describe intracellular events, such as branching, septation and translocation. Finally, completely discrete models, cellular automata, simulate the microscopic interaction among cells to reproduce emergent cooperative behaviors of large colonies. In this comment, we review a selection of models for each of these length scales, stressing their advantages and shortcomings.
dc.identifierhttps://arxiv.org/abs/q-bio/0402004
dc.identifierhttp://arxiv.org/abs/q-bio/0402004
dc.identifierComments on Theoretical Biology, 8: 563 585, 2003
dc.identifier.urihttp://salesiana.dossiersoluciones.com/handle/123456789/88261
dc.subjectPopulations and Evolution
dc.subjectCell Behavior
dc.titleMathematical modeling of filamentous microorganisms
dc.typetext

Files

Collections

arXiv