Unbalanced synaptic inhibition can create intensity-tuned auditory cortex neurons

Simple item page
dc.creatorTan, Andrew Y. Y.
dc.creatorAtencio, Craig A.
dc.creatorPolley, Daniel B.
dc.creatorMerzenich, Michael M.
dc.creatorSchreiner, Christoph E.
dc.date2006-07-21
dc.date.accessioned2026-07-07T08:02:25Z
dc.date.available2026-07-07T08:02:25Z
dc.descriptionIntensity-tuned auditory cortex neurons may be formed by intensity-tuned synaptic excitation. Synaptic inhibition has also been shown to enhance, and possibly even create intensity-tuned neurons. Here we show, using in vivo whole cell recordings in pentobarbital-anesthetized rats, that some intensity-tuned neurons are indeed created solely through disproportionally large inhibition at high intensities, without any intensity-tuned excitation. Since inhibition is essentially cortical in origin, these neurons provide examples of auditory feature-selectivity arising de novo at the cortex.
dc.description22 pages, 5 figures
dc.identifierhttps://arxiv.org/abs/q-bio/0607036
dc.identifierhttp://arxiv.org/abs/q-bio/0607036
dc.identifierNeuroscience 146: 449-462 (2007)
dc.identifierdoi:10.1016/j.neuroscience.2007.01.019
dc.identifier.urihttp://salesiana.dossiersoluciones.com/handle/123456789/129226
dc.subjectNeurons and Cognition
dc.titleUnbalanced synaptic inhibition can create intensity-tuned auditory cortex neurons
dc.typetext

Files

Collections

arXiv