A mathematical model for the therapy of the HIV infection

dc.creatorDella Rocca, G.
dc.creatorSammartino, M.
dc.creatorSeta, L.
dc.date2007-03-27
dc.date.accessioned2026-07-07T07:54:11Z
dc.date.available2026-07-07T07:54:11Z
dc.descriptionIn this paper we consider the evolution of the HIV infection under a highly effective treatment based on a combination of RTI and/or PI drugs. This is usually modelled with a set of ODEs where the drug efficacy is a constant. In this paper we consider the treatment efficacy as a dynamic variable which evolves during the treatment. To model the dynamics of the drug efficacy we use an evolutive type assumption. The resulting set of ODEs are able to reproduce the typical pattern of the illness evolution under treatment: a period of remission, which can last several years, followed by a progressive recrudescence and a viral rebound.
dc.description13 pages, 7 figures
dc.identifierhttps://arxiv.org/abs/q-bio/0703058
dc.identifierhttp://arxiv.org/abs/q-bio/0703058
dc.identifierRicerche di Matematica, 54(1), 313-327, 2005
dc.identifier.urihttp://salesiana.dossiersoluciones.com/handle/123456789/126505
dc.subjectPopulations and Evolution
dc.subjectQuantitative Methods
dc.titleA mathematical model for the therapy of the HIV infection
dc.typetext

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