Immune System -- Tumor Efficiency Rate as a new Oncological Index for Radiotherapy Treatment Optimization

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A dynamical system model for tumor -- immune system interaction together with a method to mimic radiation therapy are proposed. A large population of virtual patients is simulated following an ideal radiation treatment. A characteristic parameter, the Immune System -- Tumor Efficiency Rate (ISTER), is introduced. ISTER dependence of treatment success and other features is studied. Statistical results allow us to give a patient classification scheme. Radiotherapy treatment biological effective dose (BED) is thus optimized based on the patient physical condition, following the ALARA (As Low As Reasonably Achievable) criterion.
10 pages, 3 figures

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Populations and Evolution

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http://salesiana.dossiersoluciones.com/handle/123456789/132498

Consulte el texto completo en el siguiente enlace:

https://arxiv.org/abs/0706.0418
 http://arxiv.org/abs/0706.0418

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arXiv