Study of Non-Altered Colorectal Tissue by FT-Raman Spectroscopy

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dc.creatorAndrade, P. O.
dc.creatorBitar, R. A.
dc.creatorYassoyama, K.
dc.creatorMartinho, H.
dc.creatorSanto, A. M. E.
dc.creatorBruno, P. M.
dc.creatorMartin, A. A.
dc.date2006-07-03
dc.date.accessioned2026-07-07T07:22:47Z
dc.date.available2026-07-07T07:22:47Z
dc.descriptionFT-Raman spectroscopy was employed to study (in-vitro) non-altered human colorectal tissues aiming evaluate their spectral differences. The samples were collected from 39 patients, adding 144 spectra. The results enable one estabilish 3 well defined spectroscopic groups of what was consistently checked by statistical (clustering) and biological (histopathology) analysis. The similarity within each group was better than 90%. Groups 1 and 2 had 80% of similarity while presenting both 70% of similarity to group 3. All groups presented connective and epithelial tissues as histopathological characteristic. Group 1 differs from others by the presence of soft muscle while group 3 by presence of fatty tissue. Tissues from group 2 are composed by samples with connective and epithelial tissues. This study is very relevant in order to establish the non-altered or normal spectroscopic standard for future studies and applications on optical biopsy and diagnosis of colorectal cancer.
dc.description14 pages, 4 figures, submited to Analytical and Bioanalytical Chemistry
dc.identifierhttps://arxiv.org/abs/q-bio/0607001
dc.identifierhttp://arxiv.org/abs/q-bio/0607001
dc.identifier.urihttp://salesiana.dossiersoluciones.com/handle/123456789/115786
dc.subjectTissues and Organs
dc.subjectBiomolecules
dc.titleStudy of Non-Altered Colorectal Tissue by FT-Raman Spectroscopy
dc.typetext

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