On the internal photorelaxation mechanism of DNA

dc.creatorCzader, Arkadiusz
dc.creatorBittner, Eric R.
dc.date2008-11-04
dc.date.accessioned2026-07-07T10:15:38Z
dc.date.available2026-07-07T10:15:38Z
dc.descriptionWe propose a model for the photo-deactivation mechanism for DNA based upon accurate quantum chemical and molecular dynamical evaluations of model Watson/Crick nucleoside pairs and stacked pairs. Our results corroborate recent ultrafast experimental studies on DNA oligonucleotides and suggest that following photo-excitation to a local $π-π^*$ state, the excitation is rapidly delocalized over several (3-4) bases on an ultrafast time-scale. However, this delocalized state is unstable with respect to the motions of the protons involved in hydrogen-bonding between Watson/Crick pairs and rapidly re-localizes to a charge-transfer state on a longer time-scale ranging from 10 to 100 ps. This state, too, is unstable and relaxes via a conical intersection with the ground state near the geometry of the enol- and imino-tautomeric form. We suggest that this internal deactivation mechanism is responsible for the intrinsic photostability of DNA.
dc.description5 pages, 5 figures
dc.identifierhttps://arxiv.org/abs/0811.0625
dc.identifierhttp://arxiv.org/abs/0811.0625
dc.identifier.urihttp://salesiana.dossiersoluciones.com/handle/123456789/173233
dc.subjectSoft Condensed Matter
dc.titleOn the internal photorelaxation mechanism of DNA
dc.typetext

Files

Collections