CFinder: Locating cliques and overlapping modules in biological networks

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dc.creatorAdamcsek, Balazs
dc.creatorPalla, Gergely
dc.creatorFarkas, Illes J.
dc.creatorDerenyi, Imre
dc.creatorVicsek, Tamas
dc.date2006-02-04
dc.date.accessioned2026-07-07T07:04:11Z
dc.date.available2026-07-07T07:04:11Z
dc.descriptionSummary: Most cellular tasks are performed not by individual proteins, but by groups of functionally associated proteins, often referred to as modules. In a protein assocation network modules appear as groups of densely interconnected nodes, also called communities or clusters. These modules often overlap with each other and form a network of their own, in which nodes (links) represent the modules (overlaps). We introduce CFinder, a fast program locating and visualizing overlapping, densely interconnected groups of nodes in undirected graphs, and allowing the user to easily navigate between the original graph and the web of these groups. We show that in gene (protein) association networks CFinder can be used to predict the function(s) of a single protein and to discover novel modules. CFinder is also very efficient for locating the cliques of large sparse graphs. Availability: CFinder (for Windows, Linux, and Macintosh) and its manual can be downloaded from http://angel.elte.hu/clustering. Contact: cfinder@angel.elte.hu
dc.descriptionThe free academic research software, CFinder, used for the publication is available at the website of the publication: http://angel.elte.hu/clustering
dc.identifierhttps://arxiv.org/abs/q-bio/0602004
dc.identifierhttp://arxiv.org/abs/q-bio/0602004
dc.identifierBioinformatics 22, 1021-1023 (2006)
dc.identifierdoi:10.1093/bioinformatics/btl039
dc.identifier.urihttp://salesiana.dossiersoluciones.com/handle/123456789/109266
dc.subjectMolecular Networks
dc.subjectGenomics
dc.titleCFinder: Locating cliques and overlapping modules in biological networks
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