A helicoidal transfer matrix model for inhomogeneous DNA melting
| dc.creator | Michoel, Tom | |
| dc.creator | Van de Peer, Yves | |
| dc.date | 2005-07-25 | |
| dc.date | 2006-10-13 | |
| dc.date.accessioned | 2026-07-07T06:43:30Z | |
| dc.date.available | 2026-07-07T06:43:30Z | |
| dc.description | An inhomogeneous helicoidal nearest-neighbor model with continuous degrees of freedom is shown to predict the same DNA melting properties as traditional long-range Ising models, for free DNA molecules in solution, as well as superhelically stressed DNA with a fixed linking number constraint. Without loss of accuracy, the continuous degrees of freedom can be discretized using a minimal number of discretization points, yielding an effective transfer matrix model of modest dimension (d=36). The resulting algorithms to compute DNA melting profiles are both simple and efficient. | |
| dc.description | v3: Matlab toolbox included with source file; article unchanged, 12 pages, 11 figures, RevTeX | |
| dc.identifier | https://arxiv.org/abs/q-bio/0507036 | |
| dc.identifier | http://arxiv.org/abs/q-bio/0507036 | |
| dc.identifier | Phys. Rev. E 73, 011908 (2006) | |
| dc.identifier | doi:10.1103/PhysRevE.73.011908 | |
| dc.identifier.uri | http://salesiana.dossiersoluciones.com/handle/123456789/102437 | |
| dc.subject | Biomolecules | |
| dc.subject | Quantitative Methods | |
| dc.title | A helicoidal transfer matrix model for inhomogeneous DNA melting | |
| dc.type | text |