DMSO-Induced Dehydration of DPPC Membranes Studied by X-ray Diffraction, Small-Angle Neutron Scattering, and Calorimetry

Simple item page
dc.creatorKiselev, M. A.
dc.creatorLesieur, P.
dc.creatorKisselev, A. M.
dc.creatorGrabielle-Madelmond, C.
dc.creatorOllivon, M.
dc.date2001-08-12
dc.date.accessioned2026-07-07T05:46:11Z
dc.date.available2026-07-07T05:46:11Z
dc.descriptionThe influence of dimethyl sulfoxide (DMSO) on membrane thickness, multilamellar repeat distance, and phase transitions of 1,2-dipalmitoyl-sn-glycero-3-phosphatidylcholine (DPPC) was investigated by X-ray diffraction and small-angle neutron scattering (SANS). The differential scanning calorimetry (DSC) study of water freezing and ice melting was performed in the ternary DPPC /DMSO /water and binary DMSO /water systems. The methods applied demonstrated the differences in membrane structure in three sub-regions of the DMSO mole fraction (X_dmso): from 0.0 to 0.3 for the first, from 0.3 to 0.8 for the second, and from 0.9 to 1.0 for the third sub-region. The thickness of the intermembrane solvent at T =20C decreases from 14.4 +/- 1.8 A at X_dmso =0.0 to 7.8 +/- 1.8 A at X_dmso =0.1. The data were used to determine the number of free water molecules in the intermembrane space in the presence of DMSO. The results for 0.0 < X_dmso < 0.3 were explained in the framework of DMSO-induced dehydration of the intermembrane space.
dc.descriptionPDF: 14 pages, 9 figures; sourse in MS Word
dc.identifierhttps://arxiv.org/abs/physics/0108019
dc.identifierhttp://arxiv.org/abs/physics/0108019
dc.identifierJournal of Alloys and Compounds 286 (1999) 195-202
dc.identifier.urihttp://salesiana.dossiersoluciones.com/handle/123456789/84249
dc.subjectBiological Physics
dc.subjectSoft Condensed Matter
dc.subjectChemical Physics
dc.subjectMedical Physics
dc.titleDMSO-Induced Dehydration of DPPC Membranes Studied by X-ray Diffraction, Small-Angle Neutron Scattering, and Calorimetry
dc.typetext

Files

Collections

arXiv