SQUID-based instrumentation for ultra-low-field MRI
| dc.creator | Zotev, V. S. | |
| dc.creator | Matlashov, A. N. | |
| dc.creator | Volegov, P. L. | |
| dc.creator | Urbaitis, A. V. | |
| dc.creator | Espy, M. A. | |
| dc.creator | Kraus Jr, R. H. | |
| dc.date | 2007-05-04 | |
| dc.date | 2007-07-30 | |
| dc.date.accessioned | 2026-07-07T08:36:44Z | |
| dc.date.available | 2026-07-07T08:36:44Z | |
| dc.description | Magnetic resonance imaging at ultra-low fields (ULF MRI) is a promising new imaging method that uses SQUID sensors to measure the spatially encoded precession of pre-polarized nuclear spin populations at a microtesla-range measurement field. In this work, a seven-channel SQUID system designed for simultaneous 3D ULF MRI and magnetoencephalography (MEG) is described. The system includes seven second-order SQUID gradiometers, characterized by magnetic field resolutions of 1.2 - 2.8 fT/rtHz. It is also equipped with five sets of coils for 3D Fourier imaging with pre-polarization. Essential technical details of the design are discussed. The system's ULF MRI performance is demonstrated by multi-channel 3D images of a preserved sheep brain acquired at 46 microtesla measurement field with pre-polarization at 40 mT. The imaging resolution is 2.5 mm x 2.5 mm x 5 mm. The ULF MRI images are compared to images of the same brain acquired using conventional high-field MRI. Different ways to improve imaging SNR are discussed. | |
| dc.description | To appear in Proceedings of 11th International Superconductive Electronics Conference (ISEC 2007); 8 pages, 11 figures | |
| dc.identifier | https://arxiv.org/abs/0705.0661 | |
| dc.identifier | http://arxiv.org/abs/0705.0661 | |
| dc.identifier | Superconductor Science and Technology 20, S367 (2007) | |
| dc.identifier | doi:10.1088/0953-2048/20/11/S13 | |
| dc.identifier.uri | http://salesiana.dossiersoluciones.com/handle/123456789/140164 | |
| dc.subject | Medical Physics | |
| dc.subject | Instrumentation and Detectors | |
| dc.title | SQUID-based instrumentation for ultra-low-field MRI | |
| dc.type | text |