Heteropolymer translocation through nanopores
| dc.creator | Luo, Kaifu | |
| dc.creator | Ala-Nissila, Tapio | |
| dc.creator | Ying, See-Chen | |
| dc.creator | Bhattacharya, Aniket | |
| dc.date | 2007-01-22 | |
| dc.date.accessioned | 2026-07-07T07:56:01Z | |
| dc.date.available | 2026-07-07T07:56:01Z | |
| dc.description | We investigate the translocation dynamics of heteropolymers driven through a nanopore using a constant temperature Langevin thermostat. Specifically, we consider heteropolymers consisting of two types of monomers labeled A and B, which are distinguished by the magnitude of the driving force that they experience inside the pore. From a series of studies on polymers with sequences AnBn+m we identify both universal as well as sequence specific properties of the translocating chains. We find that the scaling of the average translocation time as a function of the chain length N remains unaffected by the heterogeneity, while the residence time of each bead is a strong function of the sequence for short repeat units. We further discover that for a symmetric heteropolymer AnBn of fixed length, the pattern exhibited by the residence time of the individual monomer has striking similarity with an interference pattern for an optical grating with N/(2n) slits. These results are relevant for designing nanopore based sequencing techniques. | |
| dc.description | 13 Pages, 6 Figures | |
| dc.identifier | https://arxiv.org/abs/cond-mat/0701522 | |
| dc.identifier | http://arxiv.org/abs/cond-mat/0701522 | |
| dc.identifier | J. Chem. Phys. 126, 145101 (2007) | |
| dc.identifier | doi:10.1063/1.2719198 | |
| dc.identifier.uri | http://salesiana.dossiersoluciones.com/handle/123456789/127158 | |
| dc.subject | Soft Condensed Matter | |
| dc.title | Heteropolymer translocation through nanopores | |
| dc.type | text |