Entropic Approach for Reduction of Amino Acid Alphabets

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dc.creatorZheng, Wei-Mou
dc.date2001-06-22
dc.date.accessioned2026-07-07T05:46:00Z
dc.date.available2026-07-07T05:46:00Z
dc.descriptionThe primitive data for deducing the Miyazawa-Jernigan contact energy or BLOSUM score metrix are the pair frequency counts. Each amino acid corresponds to a distribution. Taking the Kullback-Leibler distance of two probability distributions as resemblance coefficient and relating cluster to mixed population, we perform cluster analysis of amino acids based on the frequecy counts data. Furthermore, Ward's clustering is also obtained by adopting the average score as an objective function. An ordinal cophenetic is introduced to compare results from different clustering methods.
dc.description6 pages, 1 figure, 6 tables
dc.identifierhttps://arxiv.org/abs/physics/0106074
dc.identifierhttp://arxiv.org/abs/physics/0106074
dc.identifier.urihttp://salesiana.dossiersoluciones.com/handle/123456789/84192
dc.subjectBiological Physics
dc.subjectQuantitative Methods
dc.titleEntropic Approach for Reduction of Amino Acid Alphabets
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