Folding and Stretching in a Go-like Model of Titin

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dc.creatorCieplak, Marek
dc.creatorHoang, Trinh Xuan
dc.creatorRobbins, Mark O.
dc.date2001-12-11
dc.date.accessioned2026-07-07T02:43:48Z
dc.date.available2026-07-07T02:43:48Z
dc.descriptionMechanical stretching of the I27 domain of titin and of its double and triple repeats are studied through molecular dynamics simulations of a Go-like model with Lennard-Jones contact interactions. We provide a thorough characterization of the system and correlate the sequencing of the folding and unraveling events with each other and with the contact order. The roles of cantilever stiffness and pulling rate are studied. Unraveling of tandem titin structures has a serial nature. The force-displacement curves in this coarse-grained model are similar to those obtained through all atom calculations.
dc.description18 figures 12 pages
dc.identifierhttps://arxiv.org/abs/cond-mat/0112201
dc.identifierhttp://arxiv.org/abs/cond-mat/0112201
dc.identifier.urihttp://salesiana.dossiersoluciones.com/handle/123456789/18650
dc.subjectStatistical Mechanics
dc.subjectSoft Condensed Matter
dc.subjectBiomolecules
dc.titleFolding and Stretching in a Go-like Model of Titin
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