Miniaturised Spotter-Compatible Multicapillary Stamping Tool for Microarray Printing

Drobyshev, Alexei L; Verkhodanov, Nikolai N; Zasedatelev, Alexander S

Miniaturised Spotter-Compatible Multicapillary Stamping Tool for Microarray Printing

Authors

Drobyshev, Alexei L

Verkhodanov, Nikolai N

Zasedatelev, Alexander S

Description

Novel microstamping tool for microarray printing is proposed. The tool is capable to spot up to 127 droplets of different solutions in single touch. It is easily compatible with commercially available microarray spotters. The tool is based on multichannel funnel with polypropylene capillaries inserted into its channels. Superior flexibility is achieved by ability to replace any printing capillary of the tool. As a practical implementation, hydrogel-based microarrays were stamped and successfully applied to identify the Mycobacterium tuberculosis drug resistance.