Focal adhesion: Physics of a Biological Mechano-Sensor

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Mechanical coupling between a cell and substrate relies on focal adhesions, clusters of adhesion proteins linking stress fibers (bundles of actin proteins) inside the cell with surrounding tissue. Focal adhesions have been demonstrated to both measure and regulate the mechanical traction along the stress fibers. We present a quantitative model for focal adhesion mechano-sensing and stress regulation based on stress amplification at the critical point of a condensation transition of the adhesion proteins.
4 pages, 2 figures

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Soft Condensed Matter, Statistical Mechanics, Quantitative Biology

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http://salesiana.dossiersoluciones.com/handle/123456789/21554

Consulte el texto completo en el siguiente enlace:

https://arxiv.org/abs/cond-mat/0306116
 http://arxiv.org/abs/cond-mat/0306116
 Biophys. J. 83, 3079 (2002)

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arXiv