How shall we use the proteomics toolbox for biomarker discovery?

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dc.creatorLescuyer, Pierre
dc.creatorHochstrasser, Denis
dc.creatorRabilloud, Thierry
dc.date2008-07-08
dc.date.accessioned2026-07-07T09:49:03Z
dc.date.available2026-07-07T09:49:03Z
dc.descriptionBiomarker discovery for clinical purposes is one of the major areas in which proteomics is used. However, despite considerable effort, the successes have been relatively scarce. In this perspective paper, we try to highlight and analyze the main causes for this limited success, and to suggest alternate strategies, which will avoid them, without eluding the foreseeable weak points of these strategies. Two major strategies are analyzed, namely, the switch from body fluids to cell and tissues for the initial biomarker discovery step or, if body fluids must be analyzed, the implementation of highly selective protein selection strategies.
dc.identifierhttps://arxiv.org/abs/0807.1206
dc.identifierhttp://arxiv.org/abs/0807.1206
dc.identifierJournal of Proteome Research 6, 9 (2007) 3371-6
dc.identifierdoi:10.1021/pr0702060
dc.identifier.urihttp://salesiana.dossiersoluciones.com/handle/123456789/164443
dc.subjectGenomics
dc.titleHow shall we use the proteomics toolbox for biomarker discovery?
dc.typetext

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