Spatial signal amplification in cell biology: a lattice-gas model for self-tuned phase ordering

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dc.creatorFerraro, Teresa
dc.creatorde Candia, Antonio
dc.creatorGamba, Andrea
dc.creatorConiglio, Antonio
dc.date2007-11-20
dc.date.accessioned2026-07-07T12:19:53Z
dc.date.available2026-07-07T12:19:53Z
dc.descriptionExperiments show that the movement of eukaryotic cells is regulated by a process of phase separation of two competing enzymes on the cell membrane, that effectively amplifies shallow external gradients of chemical attractant. Notably, the cell is able to self-tune the final enzyme concentrations to an equilibrium state of phase coexistence, for a wide range of the average attractant concentration. We propose a simple lattice model in which, together with a short-range attraction between enzymes, a long-range repulsion naturally arises from physical considerations, that easily explains such observed behavior.
dc.identifierhttps://arxiv.org/abs/0711.3090
dc.identifierhttp://arxiv.org/abs/0711.3090
dc.identifierEurophysics Letters, 83, 50009 (2008)
dc.identifierdoi:10.1209/0295-5075/83/50009
dc.identifier.urihttp://salesiana.dossiersoluciones.com/handle/123456789/212916
dc.subjectStatistical Mechanics
dc.subjectCell Behavior
dc.titleSpatial signal amplification in cell biology: a lattice-gas model for self-tuned phase ordering
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