Diffusion Dynamics, Moments, and Distribution of First Passage Time on the Protein-Folding Energy Landscape, with Applications to Single Molecules

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dc.creatorLee, Chi-Lun
dc.creatorLin, Chien-Ting
dc.creatorStell, George
dc.creatorWang, Jin
dc.date2001-05-14
dc.date2002-06-20
dc.date.accessioned2026-07-07T02:41:24Z
dc.date.available2026-07-07T02:41:24Z
dc.descriptionWe study the dynamics of protein folding via statistical energy-landscape theory. In particular, we concentrate on the local-connectivity case with the folding progress described by the fraction of native conformations. We obtain information for the first passage-time (FPT) distribution and its moments. The results show a dynamic transition temperature below which the FPT distribution develops a power-law tail, a signature of the intermittency phenomena of the folding dynamics. We also discuss the possible application of the results to single-molecule dynamics experiments.
dc.identifierhttps://arxiv.org/abs/cond-mat/0105276
dc.identifierhttp://arxiv.org/abs/cond-mat/0105276
dc.identifier.urihttp://salesiana.dossiersoluciones.com/handle/123456789/17731
dc.subjectSoft Condensed Matter
dc.subjectStatistical Mechanics
dc.subjectBiomolecules
dc.titleDiffusion Dynamics, Moments, and Distribution of First Passage Time on the Protein-Folding Energy Landscape, with Applications to Single Molecules
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