Collective effects in intra-cellular molecular motor transport: coordination, cooperation and competetion

dc.creatorChowdhury, Debashish
dc.date2006-05-06
dc.date.accessioned2026-07-07T13:04:18Z
dc.date.available2026-07-07T13:04:18Z
dc.descriptionMolecular motors do not work in isolation {\it in-vivo}. We highlight some of the coordinations, cooperations and competitions that determine the collective properties of molecular motors in eukaryotic cells. In the context of traffic-like movement of motors on a track, we emphasize the importance of single-motor bio-chemical cycle and enzymatic activity on their collective spatio-temporal organisation. Our modelling strategy is based on a synthesis- the same model describes the single-motor mechano-chemistry at sufficiently low densities whereas at higher densities it accounts for the collective flow properties and the density profiles of the motors. We consider two specific examples, namely, traffic of single-headed kinesin motors KIF1A on a microtubule track and ribosome traffic on a messenger RNA track.
dc.description9 pages including LATEX text and 9 EPS figures
dc.identifierhttps://arxiv.org/abs/physics/0605053
dc.identifierhttp://arxiv.org/abs/physics/0605053
dc.identifierPhysica A 372, 84 (2006)
dc.identifierdoi:10.1016/j.physa.2006.05.005
dc.identifier.urihttp://salesiana.dossiersoluciones.com/handle/123456789/227115
dc.subjectBiological Physics
dc.subjectStatistical Mechanics
dc.subjectSubcellular Processes
dc.titleCollective effects in intra-cellular molecular motor transport: coordination, cooperation and competetion
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