On stepdown control of the false discovery proportion

dc.creatorRomano, Joseph P.
dc.creatorShaikh, Azeem M.
dc.date2006-10-27
dc.date.accessioned2026-07-07T08:08:17Z
dc.date.available2026-07-07T08:08:17Z
dc.descriptionConsider the problem of testing multiple null hypotheses. A classical approach to dealing with the multiplicity problem is to restrict attention to procedures that control the familywise error rate ($FWER$), the probability of even one false rejection. However, if $s$ is large, control of the $FWER$ is so stringent that the ability of a procedure which controls the $FWER$ to detect false null hypotheses is limited. Consequently, it is desirable to consider other measures of error control. We will consider methods based on control of the false discovery proportion ($FDP$) defined by the number of false rejections divided by the total number of rejections (defined to be 0 if there are no rejections). The false discovery rate proposed by Benjamini and Hochberg (1995) controls $E(FDP)$. Here, we construct methods such that, for any $γ$ and $α$, $P\{FDP>γ\}\le α$. Based on $p$-values of individual tests, we consider stepdown procedures that control the $FDP$, without imposing dependence assumptions on the joint distribution of the $p$-values. A greatly improved version of a method given in Lehmann and Romano \citer10 is derived and generalized to provide a means by which any sequence of nondecreasing constants can be rescaled to ensure control of the $FDP$. We also provide a stepdown procedure that controls the $FDR$ under a dependence assumption.
dc.descriptionPublished at http://dx.doi.org/10.1214/074921706000000383 in the IMS Lecture Notes--Monograph Series (http://www.imstat.org/publications/lecnotes.htm) by the Institute of Mathematical Statistics (http://www.imstat.org)
dc.identifierhttps://arxiv.org/abs/math/0610843
dc.identifierhttp://arxiv.org/abs/math/0610843
dc.identifierIMS Lecture Notes--Monograph Series 2006, Vol. 49, 33-50
dc.identifierdoi:10.1214/074921706000000383
dc.identifier.urihttp://salesiana.dossiersoluciones.com/handle/123456789/131214
dc.subjectStatistics Theory
dc.subject62J15 (Primary)
dc.titleOn stepdown control of the false discovery proportion
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