Kinetic Origin of Heredity in a Replicating System with a Catalytic Network

dc.creatorKaneko, Kunihiko
dc.date2002-03-18
dc.date.accessioned2026-07-07T05:33:59Z
dc.date.available2026-07-07T05:33:59Z
dc.descriptionThe origin of heredity is studied as a recursive state in a replicating proto-cell consisting of many molecule species in mutually catalyzing reaction networks. Protocells divide when the number of molecules, increasing due to replication, exceeds a certain threshold. We study how the chemicals in a catalytic network can form recursive production states in the presence of errors in the replication process. Depending on the balance between the total number of molecules in a cell and the number of molecule species, we have found three phases; a phase without a recursive production state, a phase with itinerancy over a few recursive states, and a phase with fixed recursive production states. Heredity is realized in the latter two phases where molecule species that are population-wise in the minority are preserved and control the phenotype of the cell. It is shown that evolvability is realized in the itinerancy phase, where a change in the number of minority molecules controls a change of the chemical state.
dc.description15 pages, to appear in J Biol. Phys
dc.identifierhttps://arxiv.org/abs/nlin/0203039
dc.identifierhttp://arxiv.org/abs/nlin/0203039
dc.identifier.urihttp://salesiana.dossiersoluciones.com/handle/123456789/80199
dc.subjectAdaptation and Self-Organizing Systems
dc.subjectSubcellular Processes
dc.titleKinetic Origin of Heredity in a Replicating System with a Catalytic Network
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