On-Off Intermittency in Time Series of Spontaneous Paroxysmal Activity in Rats with Genetic Absence Epilepsy

Hramov, A. E.; Koronovskii, A. A.; Midzyanovskaya, I. S.; Sitnikova, E.; van Rijn, C. M.

On-Off Intermittency in Time Series of Spontaneous Paroxysmal Activity in Rats with Genetic Absence Epilepsy

Authors

Hramov, A. E.

Koronovskii, A. A.

Midzyanovskaya, I. S.

Sitnikova, E.

van Rijn, C. M.

Description

Dynamic behavior of complex neuronal ensembles is a topic comprising a streamline of current researches worldwide. In this article we study the behavior manifested by epileptic brain, in the case of spontaneous non-convulsive paroxysmal activity. For this purpose we analyzed archived long-term recording of paroxysmal activity in animals genetically susceptible to absence epilepsy, namely WAG/Rij rats. We first report that the brain activity alternated between normal states and epilepsy paroxysms is the on-off intermittency phenomenon which has been observed and studied earlier in the different nonlinear systems.
11 pages, 6 figures