Transduplication resulted in the incorporation of two protein-coding sequences into the Turmoil-1 transposable element of C. elegans

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dc.creatorSela, Noa
dc.creatorStern, Adi
dc.creatorMakalowski, Wojciech
dc.creatorPupko, Tal
dc.creatorAst, Gil
dc.date2008-11-21
dc.date.accessioned2026-07-07T10:20:05Z
dc.date.available2026-07-07T10:20:05Z
dc.descriptionTransposable elements may acquire unrelated gene fragments into their sequences in a process called transduplication. Transduplication of protein-coding genes is common in plants, but is unknown of in animals. Here, we report that the Turmoil-1 transposable element in C. elegans has incorporated two protein-coding sequences into its inverted terminal repeat (ITR) sequences. The ITRs of Turmoil-1 contain a conserved RNA recognition motif (RRM) that originated from the rsp- 2 gene and a fragment from the protein-coding region of the cpg-3 gene. We further report that an open reading frame specific to C. elegans may have been created as a result of a Turmoil-1 insertion. Mutations at the 5' splice site of this open reading frame may have reactivated the transduplicated RRM motif
dc.identifierhttps://arxiv.org/abs/0811.3508
dc.identifierhttp://arxiv.org/abs/0811.3508
dc.identifierBiology Direct 2008, 3:41
dc.identifierdoi:10.1186/1745-6150-3-41
dc.identifier.urihttp://salesiana.dossiersoluciones.com/handle/123456789/174737
dc.subjectGenomics
dc.subjectPopulations and Evolution
dc.titleTransduplication resulted in the incorporation of two protein-coding sequences into the Turmoil-1 transposable element of C. elegans
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