Topological classification of RNA structures

Simple item page
dc.creatorBon, Michael
dc.creatorVernizzi, Graziano
dc.creatorOrland, Henri
dc.creatorZee, A.
dc.date2006-07-21
dc.date.accessioned2026-07-07T07:22:50Z
dc.date.available2026-07-07T07:22:50Z
dc.descriptionWe present a novel topological classification of RNA secondary structures with pseudoknots. It is based on the topological genus of the circular diagram associated to the RNA base-pair structure. The genus is a positive integer number, whose value quantifies the topological complexity of the folded RNA structure. In such a representation, planar diagrams correspond to pure RNA secondary structures and have zero genus, whereas non planar diagrams correspond to pseudoknotted structures and have higher genus. We analyze real RNA structures from the databases wwPDB and Pseudobase, and classify them according to their topological genus. We compare the results of our statistical survey with existing theoretical and numerical models. We also discuss possible applications of this classification and show how it can be used for identifying new RNA structural motifs.
dc.description17 pages, 3 tables, 13 figures (high quality figures available on request)
dc.identifierhttps://arxiv.org/abs/q-bio/0607032
dc.identifierhttp://arxiv.org/abs/q-bio/0607032
dc.identifier.urihttp://salesiana.dossiersoluciones.com/handle/123456789/115801
dc.subjectBiomolecules
dc.subjectSoft Condensed Matter
dc.subjectSubcellular Processes
dc.titleTopological classification of RNA structures
dc.typetext

Files

Collections

arXiv