Sensing DNA - DNA as nanosensor: a perspective towards nanobiotechnology

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dc.creatorMetzler, Ralf
dc.creatorAmbjoernsson, Tobias
dc.date2005-08-20
dc.date.accessioned2026-07-07T03:06:20Z
dc.date.available2026-07-07T03:06:20Z
dc.descriptionBased on modern single molecule techniques, we devise a number of possible experimental setups to probe local properties of DNA such as the presence of DNA-knots, loops or folds, or to obtain information on the DNA-sequence. Similarly, DNA may be used as a local sensor. Employing single molecule fluorescence methods, we propose to make use of the physics of DNA denaturation nanoregions to find out about the solvent conditions such as ionic strength, presence of binding proteins, etc. By measuring dynamical quantities in particular, rather sensitive nanoprobes may be constructed with contemporary instruments.
dc.description7 pages REVTeX, 7 eps figures. Journal of Computational and Theoretical Nanoscience, at press
dc.identifierhttps://arxiv.org/abs/cond-mat/0508490
dc.identifierhttp://arxiv.org/abs/cond-mat/0508490
dc.identifier.urihttp://salesiana.dossiersoluciones.com/handle/123456789/26772
dc.subjectSoft Condensed Matter
dc.titleSensing DNA - DNA as nanosensor: a perspective towards nanobiotechnology
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