Multi-strain virus dynamics with mutations: A global analysis

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dc.creatorDe Leenheer, Patrick
dc.creatorPilyugin, Sergei S.
dc.date2007-07-30
dc.date.accessioned2026-07-07T08:21:17Z
dc.date.available2026-07-07T08:21:17Z
dc.descriptionWe consider within-host virus models with more than one strain and allow mutation between the strains. If there is no mutation, a Lyapunov function establishes global stability of the steady state corresponding to the fittest strain. For small perturbations this steady state persists, perhaps with small concentrations of some or all other strains, depending on the connectivity of the graph describing all possible mutations. Moreover, using a perturbation result due to Smith and Waltman, we show that this steady state also preserves global stability.
dc.identifierhttps://arxiv.org/abs/0707.4501
dc.identifierhttp://arxiv.org/abs/0707.4501
dc.identifier.urihttp://salesiana.dossiersoluciones.com/handle/123456789/135310
dc.subjectCell Behavior
dc.titleMulti-strain virus dynamics with mutations: A global analysis
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