Bayesian Computation and Model Selection in Population Genetics

Thumbnail Image

Date

Authors

Journal Title

Journal ISSN

Volume Title

Publisher

Abstract

Description

Until recently, the use of Bayesian inference in population genetics was limited to a few cases because for many realistic population genetic models the likelihood function cannot be calculated analytically . The situation changed with the advent of likelihood-free inference algorithms, often subsumed under the term Approximate Bayesian Computation (ABC). A key innovation was the use of a post-sampling regression adjustment, allowing larger tolerance values and as such shifting computation time to realistic orders of magnitude (see Beaumont et al., 2002). Here we propose a reformulation of the regression adjustment in terms of a General Linear Model (GLM). This allows the integration into the framework of Bayesian statistics and the use of its methods, including model selection via Bayes factors. We then apply the proposed methodology to the question of population subdivision among western chimpanzees Pan troglodytes verus.
18 pages, 3 figures

Keywords

Methodology, Populations and Evolution, Computation

Citation

URI

http://salesiana.dossiersoluciones.com/handle/123456789/215953

Consulte el texto completo en el siguiente enlace:

https://arxiv.org/abs/0901.2231
 http://arxiv.org/abs/0901.2231

Collections

arXiv