Statistical Physics of Unzipping DNA

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dc.creatorNelson, David R.
dc.date2003-09-24
dc.date.accessioned2026-07-07T02:53:45Z
dc.date.available2026-07-07T02:53:45Z
dc.descriptionThe denaturation of double-stranded DNA as function of force and temperature is discussed. At room temperature, sequence heterogeneity dominates the physics of single molecule force-extension curves starting about 7 piconewtons of below a ~15 pN unzipping transition. The dynamics of the unzipping fork exhibits anomalous drift and diffusion in a similar range above this transition. Energy barriers near the transition scale as the square root of the genome size. Recent observations of jumps and plateaus in the unzipping of lambda phage DNA at constant force are consistent with these predictions.
dc.identifierhttps://arxiv.org/abs/cond-mat/0309559
dc.identifierhttp://arxiv.org/abs/cond-mat/0309559
dc.identifier.urihttp://salesiana.dossiersoluciones.com/handle/123456789/22286
dc.subjectCondensed Matter
dc.subjectBiomolecules
dc.titleStatistical Physics of Unzipping DNA
dc.typetext

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