Spectral oscillations in backscattering of light from a biological cell

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dc.creatorHeifetz, Alexander
dc.creatorPatashinski, Alexander
dc.creatorBackman, Vadim
dc.date2009-03-16
dc.date2009-03-21
dc.date.accessioned2026-07-07T12:54:31Z
dc.date.available2026-07-07T12:54:31Z
dc.descriptionPossible origins of the experimentally observed beat-like signal in elastic light backscattering from an epithelial biological cell are identified. The source of the beat-like signal is most likely the cellular nucleus, which is a spheroidal particle with an optically sharp edge, low relative index of refraction, and a size parameter in the resonant range; another possible source is an agglomeration of cell organelles of a similar size. Using Mie theory computer simulations for a dielectric sphere with biological nucleus-like parameters, we have shown that backscattering as a function of size parameter has a beat-like pattern. The high frequency periodic oscillation is the single scattering contribution, while multiple scattering events give slowly varying oscillatory contributions. With increasing contrast, the backscattering signal changes from a pure sinusoid to that of a beat signal. The beat-like pattern in scattering from a low contrast particle does not depend on any particular features of the sphere; a similar pattern is observable in scattering from star-like non-spherical objects with a sharp optical contrast and smooth shape; in this case, the high frequency of oscillations depends on the object orientation relative to incident light
dc.description14 pages, 4 figures
dc.identifierhttps://arxiv.org/abs/0903.2832
dc.identifierhttp://arxiv.org/abs/0903.2832
dc.identifier.urihttp://salesiana.dossiersoluciones.com/handle/123456789/223962
dc.subjectOptics
dc.subjectBiological Physics
dc.titleSpectral oscillations in backscattering of light from a biological cell
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