The relation of morphology and affinity maturation in germinal centers

dc.creatorMeyer-Hermann, Michael
dc.date2002-03-14
dc.date2003-06-10
dc.date.accessioned2026-07-07T05:47:11Z
dc.date.available2026-07-07T05:47:11Z
dc.descriptionThe specific morphology of germinal centers is analyzed in the context of the optimization of the humoral immune response. The relevance of dark and light zones for the affinity maturation process is investigated in the framework of a theoretical model for the germinal center reaction. Especially, it is shown that an intermediate appearance of dark zones in germinal center reactions is advantageous for the process of antibody optimization. Methodological aspects are discussed.
dc.description10 pages, 2 figures, 25 references
dc.identifierhttps://arxiv.org/abs/physics/0203045
dc.identifierhttp://arxiv.org/abs/physics/0203045
dc.identifier.urihttp://salesiana.dossiersoluciones.com/handle/123456789/84614
dc.subjectBiological Physics
dc.subjectCell Behavior
dc.titleThe relation of morphology and affinity maturation in germinal centers
dc.typetext

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