Effects of neutral selection on the evolution of molecular species

dc.creatorNewman, M. E. J.
dc.creatorEngelhardt, Robin
dc.date1997-12-15
dc.date.accessioned2026-07-07T01:50:55Z
dc.date.available2026-07-07T01:50:55Z
dc.descriptionWe introduce a new model of evolution on a fitness landscape possessing a tunable degree of neutrality. The model allows us to study the general properties of molecular species undergoing neutral evolution. We find that a number of phenomena seen in RNA sequence-structure maps are present also in our general model. Examples are the occurrence of "common" structures which occupy a fraction of the genotype space which tends to unity as the length of the genotype increases, and the formation of percolating neutral networks which cover the genotype space in such a way that a member of such a network can be found within a small radius of any point in the space. We also describe a number of new phenomena which appear to be general properties of neutrally evolving systems. In particular, we show that the maximum fitness attained during the adaptive walk of a population evolving on such a fitness landscape increases with increasing degree of neutrality, and is directly related to the fitness of the most fit percolating network.
dc.description16 pages including 4 postscript figures, typeset in LaTeX2e using the Elsevier macro package elsart.cls
dc.identifierhttps://arxiv.org/abs/adap-org/9712005
dc.identifierhttp://arxiv.org/abs/adap-org/9712005
dc.identifierProc. R. Soc. London B 265, 1333-1338 (1998)
dc.identifier.urihttp://salesiana.dossiersoluciones.com/handle/123456789/160
dc.subjectAdaptation and Self-Organizing Systems
dc.subjectQuantitative Biology
dc.titleEffects of neutral selection on the evolution of molecular species
dc.typetext

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