Is the intrinsic disorder of proteins the cause of the scale-free architecture of protein-protein interaction networks?

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dc.creatorSchnell, Santiago
dc.creatorFortunato, Santo
dc.creatorRoy, Sourav
dc.date2006-06-22
dc.date.accessioned2026-07-07T07:18:55Z
dc.date.available2026-07-07T07:18:55Z
dc.descriptionIn protein-protein interaction networks certain topological properties appear to be recurrent: networks maps are considered scale-free. It is possible that this topology is reflected in the protein structure. In this paper we investigate the role of protein disorder in the network topology. We find that the disorder of a protein (or of its neighbors) is independent of its number of protein-protein interactions. This result suggests that protein disorder does not play a role in the scale-free architecture of protein networks.
dc.description15 pages, 2 figures
dc.identifierhttps://arxiv.org/abs/q-bio/0606029
dc.identifierhttp://arxiv.org/abs/q-bio/0606029
dc.identifier.urihttp://salesiana.dossiersoluciones.com/handle/123456789/114478
dc.subjectGenomics
dc.subjectMolecular Networks
dc.titleIs the intrinsic disorder of proteins the cause of the scale-free architecture of protein-protein interaction networks?
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