Simulation of Robustness against Lesions of Cortical Networks

dc.creatorKaiser, Marcus
dc.creatorMartin, Robert
dc.creatorAndras, Peter
dc.creatorYoung, Malcolm P.
dc.date2007-04-03
dc.date.accessioned2026-07-07T09:58:18Z
dc.date.available2026-07-07T09:58:18Z
dc.descriptionStructure entails function and thus a structural description of the brain will help to understand its function and may provide insights into many properties of brain systems, from their robustness and recovery from damage, to their dynamics and even their evolution. Advances in the analysis of complex networks provide useful new approaches to understanding structural and functional properties of brain networks. Structural properties of networks recently described allow their characterization as small-world, random (exponential) and scale-free. They complement the set of other properties that have been explored in the context of brain connectivity, such as topology, hodology, clustering, and hierarchical organization. Here we apply new network analysis methods to cortical inter-areal connectivity networks for the cat and macaque brains. We compare these corticocortical fibre networks to benchmark rewired, small-world, scale-free and random networks, using two analysis strategies, in which we measure the effects of the removal of nodes and connections on the structural properties of the cortical networks. The brain networks' structural decay is in most respects similar to that of scale-free networks. The results implicate highly connected hub-nodes and bottleneck connections as structural basis for some of the conditional robustness of brain systems. This informs the understanding of the development of brain networks' connectivity.
dc.descriptionsubmitted to European Journal of Neuroscience (under review)
dc.identifierhttps://arxiv.org/abs/0704.0392
dc.identifierhttp://arxiv.org/abs/0704.0392
dc.identifierEuropean Journal of Neuroscience, 25:3185--3192, 2007
dc.identifierdoi:10.1111/j.1460-9568.2007.05574.x
dc.identifier.urihttp://salesiana.dossiersoluciones.com/handle/123456789/167669
dc.subjectNeurons and Cognition
dc.subjectDisordered Systems and Neural Networks
dc.subjectPhysics and Society
dc.titleSimulation of Robustness against Lesions of Cortical Networks
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