Mechanism of antifreeze proteins action, based on Hierarchic theory of water and new ''clusterphilic'' interaction

dc.creatorKaivarainen, Alex
dc.date2001-05-20
dc.date.accessioned2026-07-07T05:45:51Z
dc.date.available2026-07-07T05:45:51Z
dc.descriptionA basically new Hierarchic theory, general for solids and liquids (Kaivarainen, 2001, 2000, 1995, 1992), has been briefly described and illustrated by computer simulations on examples of water and ice. Full description of theory and its numerous applications are presented in series of articles at the arXiv of Los-Alamos (see http://arXiv.org/abs/physics/0102086). New clusterphilic interactions, intermediate between hydrophilic and hydrphobic, are introduced. They can be subdivided into: intramolecular - when water cluster is localized in the ''open'' states of big interdomain or intersubunit cavities and intermolecular clusterphilic interactions. Intermolecular clusterphilic interactions can be induced by very different macromolecules. The latter displays themselves in bordering of water cluster by macromolecules and forming so-called ''clustrons''. Clusterphilic interactions can play an important role in self-organization of biosystems, especially multiglobular allosteric enzymes, microtubules and the actin filaments. The selected review of literature, devoted to antifreeze proteins (AFP) and ice-nucleation proteins (INP) interaction with water is presented. Corresponding experimental results were analyzed on the base of Hierarchic theory. The possible mechanism of cryoproteins influence on water, changing its freezing point has been proposed. The consequences of new model of AFP action and ways of its experimental verification are described also.
dc.descriptionFor additional information see http://www.karelia.ru/~alexk
dc.identifierhttps://arxiv.org/abs/physics/0105067
dc.identifierhttp://arxiv.org/abs/physics/0105067
dc.identifier.urihttp://salesiana.dossiersoluciones.com/handle/123456789/84137
dc.subjectGeneral Physics
dc.titleMechanism of antifreeze proteins action, based on Hierarchic theory of water and new ''clusterphilic'' interaction
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