Modeling of negative autoregulated genetic networks in single cells

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dc.creatorLipshtat, Azi
dc.creatorPerets, Hagai B.
dc.creatorBalaban, Nathalie Q.
dc.creatorBiham, Ofer
dc.date2005-04-26
dc.date.accessioned2026-07-07T06:40:40Z
dc.date.available2026-07-07T06:40:40Z
dc.descriptionWe discuss recent developments in the modeling of negative autoregulated genetic networks. In particular, we consider the temporal evolution of the population of mRNA and proteins in simple networks using rate equations. In the limit of low copy numbers, fluctuation effects become significant and more adequate modeling is then achieved using the master equation formalism. The analogy between regulatory gene networks and chemical reaction networks on dust grains in the interstellar medium is discussed. The analysis and simulation of complex reaction networks are also considered.
dc.description15 pages, 4 figures. Published in Gene
dc.identifierhttps://arxiv.org/abs/q-bio/0504030
dc.identifierhttp://arxiv.org/abs/q-bio/0504030
dc.identifierGene, Vol. 347, Issue 2, 14 March 2005, Pages 265-271
dc.identifierdoi:10.1016/j.gene.2004.12.016
dc.identifier.urihttp://salesiana.dossiersoluciones.com/handle/123456789/101453
dc.subjectMolecular Networks
dc.subjectBiological Physics
dc.titleModeling of negative autoregulated genetic networks in single cells
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